Social Stress and the Inflamed Brain

Apr. 21, 2013 —

Science Daily/Federation of American Societies for Experimental Biology

Depression is the leading cause of disability with more than 350 million people globally affected by this disease. In addition to debilitating consequences on mental health, depression predisposes an individual to physiological disease such as heart disease, and conversely heart disease increases the risk of depression.

According to the World Health Organization by the year 2020 heart disease and depression will be the number one and number two leading causes of disability in developed countries. While the co-occurrence of these disorders is well recognized, an understanding of the underlying mechanisms that lead to this relationship are lacking.

The identification of factors in the brain that distinguish susceptibility and resiliency to depression and heart disease comorbidity would be a major advance in predicting, preventing and treating these disorders. Dr. Wood is continuing these studies as an Assistant Professor at the University of South Carolina School of Medicine with the hope that these findings will uncover new targets to treat the mind and body.

http://www.sciencedaily.com/releases/2013/04/130421153839.htm