Study of one million Danish children: Childhood adversity increases the risk of early death
August 19, 2020
Science Daily/University of Copenhagen The Faculty of Health and Medical Sciences
In many ways, our childhood lays the foundation of our health in adult life. It is central to our physical and cognitive development. If this development is disturbed, it may have long-term consequences for our physical and mental health later in life.
In a new study, researchers from the Faculty of Health and Medical Sciences at the University of Copenhagen show that adversity in childhood increases the risk of premature death in early adulthood (16-36 years of age).
The researchers have recorded social and stressful adversity* in childhood among one million Danish children.
'We divided the children into five groups depending on the degree of adversity experienced in childhood. The more stressful experiences they have experienced during childhood, the higher the mortality rate in early adulthood. For the most vulnerable children, the mortality rate is surprisingly 4.5 times higher', says Professor Naja Hulvej Rod from the Department of Public Health.
The higher mortality rate mainly manifests itself in suicide and accidents, but the study also shows a higher risk of dying from cancer in this group.
Poverty in Childhood Does Not Rhyme with Welfare State
According to the researchers, the results of the study stress the critical importance of broad structural public-health initiatives to reduce stressful adversity in childhood. For example, prevention of childhood poverty and other adversity in childhood. With time, it may help reduce social inequality in health.
'It is striking to see such a strong connection between adversity in childhood and mortality in the Danish welfare state, which among other things aims to promote financial stability among families with young children and to minimise social adversity. From an international perspective, you may worry that these associations are even stronger in a less extensive welfare system', says Naja Hulvej Rod.
The study is the first of its kind on a global basis. The size of the study has made it possible for the researchers to study the associations between incidents of social and stressful adversity throughout childhood and how it affects mortality rates among young adults.
*In the study, social adversity is defined as financial poverty or long-term unemployment in the family, while stressful adversity includes e.g. death of a parent, divorce or alcohol/drug abuse among the parents.
Group 1: 54 % of the children experienced no or only very few isolated incidents of adversity in childhood.
Groups 2-4: 43 % of the children experienced isolated incidents of adversity in childhood, mainly related to poverty or illness in the family. Here the researchers found a mortality rate in early adulthood that is 1.3-1.8 times higher than in Group 1.
Group 5: 3 % experienced great social and stressful adversity throughout childhood. In this group, the mortality rate is 4.5 times higher than in Group 1.
https://www.sciencedaily.com/releases/2020/08/200819094805.htm
For kids who face trauma, good neighbors or teachers can save their longterm health
September 16, 2019
Science Daily/Brigham Young University
New research shows just how important positive childhood experiences are for our long-term health -- especially for those who experience significant adversity as a child.
Studies over the past 20 years have found a correlation between the number of adverse childhood events (such as death or divorce) and worse health outcomes later in life. A new study from professor Ali Crandall and other Brigham Young University coauthors discovered that positive childhood experiences -- like having good neighbors, regular meals or a caregiver you feel safe with -- have the potential to negate harmful health effects caused by adverse childhood experiences.
"If your child has experienced trauma and you're worried about the long-term impact it could have on them, these findings show that the positive experiences in childhood lead to better adult physical and mental health, no matter what they have faced," said Crandall, assistant professor of public health at BYU.
Specifically, the study found that even when an individual had four or more adverse childhood experiences (called ACEs), having a high number of advantageous childhood experiences (Counter-ACEs) lessened the negative effect of ACEs on adult health. This is significant because the landmark 1998 ACEs study concluded that having four or more ACEs in childhood greatly increases negative health outcomes, including higher BMI, smoking rates, depression and chronic health conditions.
BYU study participants reported the number of ACEs and Counter-ACEs they experienced in childhood. ACEs include abuse, abandonment, having a family member in jail, alcoholism, mental illness, addiction, divorce or death. The full list of Counter-ACEs includes having good friends and neighbors, beliefs that provide comfort, liking school, teachers who care, having a caregiver whom you feel safe with, opportunities to have fun, feeling comfortable with yourself and a predictable home routine like regular meals and bedtimes.
Accoring to the study findings, published recently in the journal Child Abuse & Neglect, nearly 75 percent of participants had at least one adverse childhood experience, while the average amount of ACEs was 2.67 per person. The average positive experience score was 8.15, with 39 percent of people having experienced all 10 of those Counter-ACEs.
Participants also reported their current health through a variety of physical measures -- like BMI, fruit and vegetable consumption, physical exercise, sleep difficulties and if they smoked daily -- as well as their cognitive and mental health through executive functioning abilities, perceived stress, depression, internal locus of control, gratitude, forgiveness of self and challenging situations and familial closeness. Interestingly, researchers also found that the absence of Counter-ACEs led to poor adult health regardless of the number of ACEs.
"As bad as ACEs may be, the absence of these positive childhood experiences and relationships may actually be more detrimental to lifelong health so we need more focus on increasing the positive," Crandall said.
While many of the adverse childhood experiences in this study are affected by a child's family situation, Crandall said that "other adults in a child's life that are not the parent, like extended family, teachers, neighbors, friends and youth leaders all help to increase the number of counter ACEs and boosts lifelong health."
Crandall believes that increasing counter-ACES in the home is the easiest place to start and is working to educate the community about how to do this in conjunction with United Way. BYU professors Brianna Magnusson, Len Novilla, Carl Hanson and Michael Barnes were coauthors on the study.
https://www.sciencedaily.com/releases/2019/09/190916144004.htm
Early-life challenges affect how children focus, face the day
June 5, 2019
Science Daily/University of Washington
Experiences such as poverty, residential instability, or parental divorce or substance abuse, can affect executive function and lead to changes in a child's brain chemistry, muting the effects of stress hormones, according to a new study.
Adversity early in life tends to affect a child's executive function skills -- their ability to focus, for example, or organize tasks.
Experiences such as poverty, residential instability, or parental divorce or substance abuse, also can lead to changes in a child's brain chemistry, muting the effects of stress hormones. These hormones rise to help us face challenges, stress or to simply "get up and go."
Together, these impacts to executive function and stress hormones create a snowball effect, adding to social and emotional challenges that can continue through childhood. A new University of Washington study examines how adversity can change the ways children develop.
"This study shows how adversity is affecting multiple systems inside a child," said the study's lead author, Liliana Lengua, a UW professor of psychology and director of the Center for Child and Family Well-Being. "The disruption of multiple systems of self-control, both intentional planning efforts and automatic stress-hormone responses, sets off a cascade of neurobiological effects that starts early and continues through childhood."
The study, published May 10 in Development and Psychopathology, evaluated 306 children at intervals over more than two years, starting when participants were around 3 years old, up to age 5 ½. Children were from a range of racial, ethnic and socioeconomic backgrounds, with 57% considered lower income or near poverty.
Income was a key marker for adversity. In addition, the children's mothers were surveyed about other risk factors that have been linked to poor health and behavior outcomes in children, including family transitions, residential instability, and negative life events such as abuse or the incarceration of a parent.
Against these data, Lengua's team tested children's executive function skills with a series of activities, and, through saliva samples, a stress-response hormone called diurnal cortisol.
The hormone that "helps us rise to a challenge," Lengua said, cortisol tends to follow a daily, or diurnal, pattern: It increases early in the morning, helping us to wake up. It is highest in the morning -- think of it as the energy to face the day -- and then starts to fall throughout the day. But the pattern is different among children and adults who face constant stress, Lengua said.
"What we see in individuals experiencing chronic adversity is that their morning levels are quite low and flat through the day, every day. When someone is faced with high levels of stress all the time, the cortisol response becomes immune, and the system stops responding. That means they're not having the cortisol levels they need to be alert and awake and emotionally ready to meet the challenges of the day," she said.
To assess executive function, researchers chose preschool-friendly activities that measured each child's ability to follow directions, pay attention and take actions contrary to impulse. For instance, in a game called "Head-Toes-Knees-Shoulders," children are told to do the opposite of what a researcher tells them to do -- if the researcher says, "touch your head," the child is supposed to touch their toes. In another activity, children interact with two puppets -- a monkey and a dragon -- but are supposed to follow only the instructions given by the monkey.
When children are better at following instructions in these and similar activities, they tend to have better social skills and manage their emotions when stressed. Children who did well on these tasks also tended to have more typical patterns of diurnal cortisol.
But children who were in families that had lower income and higher adversity tended to have both lower executive function and an atypical diurnal cortisol pattern. Each of those contributed to more behavior problems and lower social-emotional competence in children when they were about to start kindergarten.
The study shows that not only do low income and adversity affect children's adjustment, but they also impact these self-regulation systems that then add to children's adjustment problems. "Taken all together, it's like a snowball effect, with adverse effects adding together," Lengua said.
While past research has pointed to the effects of adversity on executive function, and to the specific relationship between cortisol and executive function, this new study shows the additive effects over time, Lengua said.
"Executive function is an indicator that shows the functioning of cognitive regulation. Cortisol is the neuroendocrine response, an automatic response, and the two consistently emerge as being related to each other and impacting behavior in children," she said.
The research could be used to inform parenting programs, early childhood and school-based interventions, Lengua said. Safe, stable environments and communities, and positive, nurturing parenting practices support child development, while a focus on relationships and healthy behaviors in preschool settings can support children of all backgrounds -- those with high as well as low adversity.
https://www.sciencedaily.com/releases/2019/06/190605171354.htm