Working memory positively associated with higher physical endurance, better cognitive function

Suboptimal cardiovascular health, smoking are associated with less cohesive brain network

December 5, 2017

Science Daily/The Mount Sinai Hospital / Mount Sinai School of Medicine

A positive relationship has been found between the brain network associated with working memory -- the ability to store and process information relevant to the task at hand -- and healthy traits such as higher physical endurance and better cognitive function

These traits were associated with greater cohesiveness of the working memory brain network while traits indicating suboptimal cardiovascular and metabolic health, and suboptimal health habits including binge drinking and regular smoking, were associated with less cohesive working memory networks.

This is the first study to establish the link between working memory and physical health and lifestyle choices.

The results of the study will be published online in Molecular Psychiatry.

The research team took brain scans of 823 participants in the Human Connectome Project (HCP), a large brain imaging study funded by the National Institutes of Health, while they performed a task involving working memory, and extracted measures of brain activity and connectivity to create a brain map of working memory. The team then used a statistical method called sparse canonical correlation to discover the relationships between the working memory brain map and 116 measures of cognitive ability, physical and mental health, personality, and lifestyle choices. They found that cohesiveness in the working memory brain map was positively associated with higher physical endurance and better cognitive function. Physical traits such as high body mass index, and suboptimal lifestyle choices including binge alcohol drinking and regular smoking, had the opposite association.

"Working memory accounts for individual differences in personal, educational, and professional attainment," said Sophia Frangou, MD, PhD, Professor of Psychiatry at the Icahn School of Medicine at Mount Sinai. "Working memory is also one of the brain functions that is severely affected by physical and mental illnesses. Our study identified factors that can either support or undermine the working memory brain network. Our findings can empower people to make informed choices about how best to promote and preserve brain health."

https://www.sciencedaily.com/releases/2017/12/171205091531.htm

Physical activity linked to lower rates of cognitive impairment

July 19, 2011

Science Daily/JAMA and Archives Journals

Engaging in regular physical activity is associated with less decline in cognitive function in older adults, according to two studies published Online First by Archives of Internal Medicine, one of the JAMA/Archives journals. The articles are being released on July 19 to coincide with the International Conference on Alzheimer's Disease in Paris and will be included in the July 25 print edition

In one article, Marie-Noël Vercambre, Ph.D., from the Foundation of Public Health, Mutuelle Generale de l'Education Nationale, Paris, and colleagues examined data from the Women's Antioxidant Cardiovascular Study, which included women who had either prevalent vascular disease or three or more coronary risk factors. The researchers determined patients' physical activity levels at baseline (1995 to 1996) and every two years thereafter. Between 1998 and 2000, they conducted telephone interviews with 2,809 women; the calls included tests of cognition, memory and category fluency, and followed up the tests three more times over the succeeding 5.4 years.

http://www.sciencedaily.com/releases/2011/07/110719101755.htm