Frequent cannabis users are way too high ... in their estimates of cannabinoids

In study at Hash Bash, frequent users reported low knowledge of, and substantially overestimated, cannabinoid content

April 15, 2020

Science Daily/University at Buffalo

Researchers surveyed nearly 500 Hash Bash attendees, asking them to fill out a 24-item questionnaire. Participants were asked to fill in, in milligrams, the amounts they considered to be effective doses of THC and CBD. They were way off.

One would think that cannabis enthusiasts attending a marijuana advocacy event would be knowledgeable about cannabinoids.

Not necessarily, according to the findings of a study by researchers from the University at Buffalo and the University of Michigan, who surveyed frequent cannabis users at an annual marijuana advocacy event held on the University of Michigan campus.

The surprisingly low level of knowledge about tetrahydrocannabinol (THC) and cannabidiol (CBD) content, and effective dosages, demonstrated by Hash Bash participants highlights the need for additional public health education and research, according to Daniel Kruger, PhD, the lead author of the study, published online ahead of print today in the journal Drugs: Education, Prevention and Policy.

"Even the people who are most enthusiastic have very poor knowledge of cannabinoid content. They greatly overestimated how much THC and how much CBD was in various strains, and what the effective dosages were," said Kruger, a research associate professor of community health and health behavior in the UB's School of Public Health and Health Professions. He is also a research investigator with the Population Studies Center at the University of Michigan.

Researchers surveyed nearly 500 Hash Bash attendees, asking them to fill out a 24-item questionnaire. Two-thirds of participants reported using cannabis every day, and most said it was for health or medical purposes. More than three-quarters of survey-takers said their knowledge of cannabis came from their own experiences.

The study survey asked participants to fill in, in milligrams, the amounts they considered to be effective doses of THC and CBD. (THC is the principal psychoactive compound and the one largely responsible for the high experienced by users. CBD does not have the same psychoactivity, but has other effects, such as reduction of anxiety.) Participants could also check the box for "I don't know."

The majority reported they didn't know. Other participants gave average estimates of 91 milligrams for THC and 177 milligrams for CBD. In other words, they were way off.

"The average estimate for an effective dose of THC would actually be fatal in humans," Kruger said.

One participant even said 1 million milligrams was the effective dose for THC. "That's a kilogram of THC. That's enough to fill an entire football stadium full of people and get them all high," Kruger said.

Participants also were asked to fill in what they thought were the percentages for high and low THC strains, and high and low CBD strains. The majority (58%) believed that a low-THC strain of cannabis was 20% THC or higher -- a level that would actually be considered a high-THC strain. In addition, 22% believed that a low-THC strain of cannabis was 40% THC or higher, which exceeds the levels of anything available now.

For CBD, 86% felt that a low strain of cannabis was 10% CBD or higher, a level considered representative of a high-CBD strain of cannabis. Nearly half believed that a low strain was 30% CBD or higher, which exceeds the CBD level of any existing strain.

"Our results suggest the need for broad-based cannabis education programs to help advocates and the general public to better understand and manage their use of the drug," said study co-author, R. Lorraine Collins, PhD, associate dean for research in UB's School of Public Health and Health Professions.

The current paper is the latest in a series of studies Kruger and his UB colleagues have published in recent years, based on data collected at Hash Bash. Their findings have shown how little many cannabis users know about the drug. The researchers also have highlighted the lackluster public health efforts to promote an effective harm reduction approach to marijuana use, especially during an era when cannabis is being deregulated in many states.

The stakes are higher with an increasing percentage of Americans using cannabis for a variety of recreational and medical reasons, as well as increasing cannabis potency, researchers say.

"Cannabis strains are 20 times as potent today as they were during the Summer of Love," said study co-author Jessica Kruger, PhD, clinical assistant professor of community health and health behavior in UB's School of Public Health and Health Professions.

The main message: "We really have to educate people. This has very real consequences, because these compounds have differential effects," Daniel Kruger said.

"Most Americans now live in a state where cannabis is legal, at least for medical purposes, but the information channels aren't there regarding safe and effective cannabis use."

https://www.sciencedaily.com/releases/2020/04/200415133416.htm

Daily cannabis use is on the rise among American adults

June 20, 2018

Science Daily/Columbia University's Mailman School of Public Health

Cannabis use may be decreasing among teens, but a new study by researchers at Columbia University's Mailman School of Public Health showed that American adults have increasingly used cannabis daily since 2007. The findings are published online in the Journal of Studies on Alcohol and Drugs.

The legal status of cannabis for medicinal and recreational use rapidly evolved between 2007 and 2014, with the number of states with medical cannabis laws doubling from 12 to 24. As of September 2017, 29 states and the District of Columbia had medical cannabis laws, and 8 states and the District of Columbia had recreational cannabis laws.

The study found that nondaily cannabis use decreased among those aged 12 to 2J and 35 to 49 before 2007, increased among all adults after 2007, particularly among adults 26 to 34 -- the latter by 4.5 percent. Daily cannabis use decreased among those 12 to 17 years of age before 2007 and increased among adults in general after 2007. Daily cannabis use was highest among 18 to 34-year-olds but overall, the rate of daily cannabis use increase did not differ significantly and ranged between one and two percentage points among adults 18 to 54.

"Increases in daily and nondaily cannabis use among adults after 2007 could be due to increasingly permissive cannabis legislation, attitudes, and lower risk perception," said Pia M. Mauro, PhD, assistant professor of Epidemiology at the Mailman School of Public Health and first author.

Using the National Survey on Drug Use and Health, a survey of individuals ages 12 and older, the researchers examined trends in cannabis use among six age categories between 2002 and 2014. They compared change over time to identify ages that may have disproportionately increased use of cannabis. Daily use was defined as 300 days or more in the past year.

"We saw a steady increase in more frequent use among people who reported cannabis use, including young people," Mauro noted. "We found significant increases in daily cannabis use across adult age categories after 2007 that contrasted with stable prevalence before 2007 and decreases among adolescents."

"Not all adults use cannabis at the same rate," said Silvia Martins, MD, PhD, Mailman School associate professor of Epidemiology and senior author. "Understanding the ages at which young people and adults use cannabis can help target appropriate reduction or prevention interventions."

Middle-age adults ages 50 to 64 were the only group with increases in nondaily cannabis use both before and after 2007. If trends continue, prevalence estimates of cannabis use among ages 50 to 64 could surpass those of adults ages 35 to 49.

"Research about the patterns and consequences of cannabis use in baby boomers in particular is needed, since use is high in this birth cohort and is expected to continue to increase," said Martins. "Moreover, significant increases in nondaily cannabis use among adults 65 and older defy perceptions that older adults do not use cannabis, although daily use in this age group remains rare."

The study was funded by the National Institute on Drug Abuse (grants T32DA031099, R01DA037866, and R01DA034244); and the New York State Psychiatric Institute. The authors report no competing interests.

Co-authors are Hannah Carliner, Qiana Brown, and Melanie Wall, Mailman School of Public Health; Deborah Hasin, Mailman School of Public Health and New York State Psychiatric Institute; Dvora Shmulewitz, Reanne Rahim-Juwel, and Aaron Sarvet, New York State Psychiatric Institute and Department of Psychiatry, Columbia University Irving Medical Center.

https://www.sciencedaily.com/releases/2018/06/180620125904.htm