Pathways linking childhood stressors and socioeconomic status to longevity

September 18, 2019

Science Daily/Boston University School of Medicine

New research has found that individuals raised in families with higher socioeconomic status were more optimistic in midlife, and in turn, lived longer. Those who experienced more psychosocial stressors, such as parental death, frequent moves and harsh discipline, tended to encounter more stressful life events in midlife, and had greater risk of dying.

After years of generalized theories and hypothesis, research has finally pinpointed certain aspects of childhood experience linked to people living longer.

Individuals raised in families with higher socioeconomic status were more optimistic in midlife, and in turn, lived longer. Those who experienced more psychosocial stressors, such as parental death, frequent moves and harsh discipline, tended to encounter more stressful life events in midlife, and had greater risk of dying.

Prior research has shown that adverse childhood experiences are associated with higher mortality risk. However, the effects appear to be driven by a small proportion of individuals who experienced multiple "hits" of severe stressors, such as physical abuse and domestic violence. Little is known about the potential effects of milder but more common stressors and the potential benefits of favorable childhood experiences on longevity. How different aspects of childhood experiences come to influence life span has rarely been studied. These questions are addressed in a new study in the journal Psychology and Aging.

The study involved 1,042 men who had been followed since 1961 in the Normative Aging Study. Three aspects of childhood experiences, including socioeconomic status, psychosocial stressors and presence of close relationships were assessed at study entry and in 1995. Optimism, life satisfaction, stressful life events and negative affect in midlife were assessed from 1985-91. Mortality status was tracked through 2016.

A key finding was that men who recalled having more childhood stressors also tended to experience more stressors as adults, and in turn, had greater risk of dying. For example, when comparing men who had five versus one childhood psychosocial stressors, those with more childhood stressors had a three percent greater risk of dying that was due to having more adulthood stressors. These finding suggest that a continuous pattern of stressor exposure from childhood to midlife may act as a precursor to reduced lifespan.

The researchers also looked at whether and how favorable aspects of childhood experiences may contribute to longevity. In particular, men raised in families with higher socioeconomic status tended to report higher levels of optimism and life satisfaction in midlife, and in turn, had greater likelihood of having longer lives. These findings suggest that optimism and life satisfaction are resilience pathways which convey the benefits of childhood socioeconomic resources onto longer lives.

"Our findings offer novel evidence on unique and shared pathways linking specific dimensions of early life experiences to longevity," said corresponding author Lewina Lee, PhD, clinical research psychologist at the National Center for PTSD at VA Boston and assistant professor of psychiatry at Boston University School of Medicine. "We hope that our research will stimulate further work to identify and intervene on factors which lie on the pathways linking childhood experiences to later-life health."

https://www.sciencedaily.com/releases/2019/09/190918122459.htm

Some children are more likely to suffer depression long after being bullied

July 1, 2019

Science Daily/University of Bristol

Some young adults who were bullied as a child could have a greater risk of ongoing depression due to a mix of genetic and environmental factors according to a new study from the University of Bristol.

Researchers wanted to find out what factors influenced depression in young adults between the ages of 10 and 24 and why some people responded differently to risk factors such as bullying, maternal postnatal depression, early childhood anxiety and domestic violence.

Using detailed mood and feelings questionnaires and genetic information from 3,325 teenagers who are part of Bristol's Children of the 90s study, alongside evidence of these risk factors at nine points in time they found that childhood bullying was strongly associated with trajectories of depression that rise at an early age. Children who continued to show high depression into adulthood were also more likely to have genetic liability for depression and a mother with postnatal depression. However, Children who were bullied but did not have any genetic liability for depression showed much lower depressive symptoms as they become young adults.

University of Bristol PhD student Alex Kwong commented: "Although we know that depression can strike first during the teenage years we didn't know how risk factors influenced change over time. Thanks to the Children of the 90s study, we were able to examine at multiple time points the relationships between the strongest risk factors such as bullying and maternal depression, as well as factors such as genetic liability.

"It's important that we know if some children are more at risk of depression long after any childhood bullying has occurred. Our study found that young adults who were bullied as children were eight times more likely to experience depression that was limited to childhood. However, some children who were bullied showed greater patterns of depression that continued into adulthood and this group of children also showed genetic liability and family risk.

"However, just because an individual has genetic liability to depression does not mean they are destined to go on and have depression. There are a number of complex pathways that we still don't fully understand and need to investigate further.

"The next steps should continue to look at both genetic and environmental risk factors to help untangle this complex relationship that would eventually help influence prevention and coping strategies for our health and education services."

Lecturer in Psychiatric Epidemiology at the University of Bristol Dr Rebecca Pearson added: "The results can help us to identify which groups of children are most likely to suffer ongoing symptoms of depression into adulthood and which children will recover across adolescence. For example, the results suggest that children with multiple risk factors (including family history and bullying) should be targeted for early intervention but that when risk factors such as bullying occur insolation, symptoms of depression may be less likely to persist"

Karen Black, Chief Executive Officer for Bristol's Off the Record added: "At Off The Record we see a diverse mix of young people presenting with a range of needs, often depression and anxiety. Understanding some of the factors that influence this will further help us to shape services and our offer for young people. I would also hope that studies such as these will help change policy direction and spending so that we start to get upstream of the issues that we know affect mental health including education and family, prevention rather than cure ideally."

https://www.sciencedaily.com/releases/2019/07/190701144454.htm

Psychedelic drugs may reduce domestic violence

April 26, 2016

Science Daily/University of British Columbia

Psychedelic drugs may help curb domestic violence committed by men with substance abuse problems, according to a new UBC study.

The UBC Okanagan study found that 42 per cent of U.S. adult male inmates who did not take psychedelic drugs were arrested within six years for domestic battery after their release, compared to a rate of 27 per cent for those who had taken drugs such as LSD, psilocybin (commonly known as magic mushrooms) and MDMA (ecstasy).

The observational study followed 302 inmates for an average of six years after they were released. All those observed had histories of substance use disorders.

"While not a clinical trial, this study, in stark contrast to prevailing attitudes that views these drugs as harmful, speaks to the public health potential of psychedelic medicine," says Assoc. Prof. Zach Walsh, the co-director for UBC Okanagan's Centre for the Advancement of Psychological Science and Law. "As existing treatments for intimate partner violence are insufficient, we need to take new perspectives such as this seriously."

"Intimate partner violence is a major public health problem and existing treatments to reduce reoffending are insufficient," he says. "With proper dosage, set, and setting we might see even more profound effects. This definitely warrants further research."

The study was co-authored by University of Alabama Assoc. Prof. Peter Hendricks, who predicts that psilocybin and related compounds could revolutionize the mental health field.

"Although we're attempting to better understand how or why these substances may be beneficial, one explanation is that they can transform people's lives by providing profoundly meaningful spiritual experiences that highlight what matters most," says Hendricks. "Often, people are struck by the realization that behaving with compassion and kindness toward others is high on the list of what matters."

While research on the benefits of psychedelic drugs took place in the 1950 to the 1970s, primarily to treat mental illness, it was stopped due to the reclassification of the drugs to a controlled substance in the mid-1970s. Recent years have seen a resurgence of interest in psychedelic medicine.

"The experiences of unity, positivity, and transcendence that characterize the psychedelic experience may be particularly beneficial to groups that are frequently marginalized and isolated, such as the incarcerated men who participated in this study," says Walsh.

The study was published last week in the Journal of Psychopharmacology.

https://www.sciencedaily.com/releases/2016/04/160426091744.htm

Impact of domestic violence on women's mental health

March 31, 2015

Science Daily/University of Montreal

In addition to their physical injuries, women who are victims of domestic violence are also at a greater risk of mental health problems such as depression and psychotic symptoms. "We studied the impact of domestic violence on the risk of mental health problems, particularly depression," explained the first study author. "We also studied the role of certain factors from the victims' personal history, such as childhood abuse and economic poverty," she explained.

"We studied the impact of domestic violence on the risk of mental health problems, particularly depression," explained Isabelle Ouellet-Morin, first study author and a researcher at the Institut universitaire en santé mentale de Montréal. "We also studied the role of certain factors from the victims' personal history, such as childhood abuse and economic poverty," explained Ms. Ouellet-Morin, who is also a professor at the School of Criminology at the University of Montreal.

1,052 mothers participated in the Environmental Risk (E-Risk) Longitudinal Twin Study over 10 years. Only subjects with no previous history of depression were considered for the study. Over this decade, the researchers conducted multiple interviews to determine whether the subjects had suffered violence from their spouses and whether they suffered from mental health disorders.

Results

• ·      More than one third of the women reported suffering violence from their spouses (e.g., being pushed or hit with an object).
• ·      These women had a more extensive history of childhood abuse, abuse of illicit substances, economic poverty, early pregnancy, and an antisocial personality.
• ·      They were twice as likely to suffer from depression, even when controlling for the impact of childhood abuse.
• ·      Domestic violence had an impact not just on mood but on other mental health aspects as well. These women had a three times higher risk of developing schizophrenia-like psychotic symptoms. This risk doubled for women who were also victims of childhood abuse.

"Domestic violence is unacceptable because of the injuries it causes. We have shown that these injuries are not only physical: they can also be psychological, as they increase the risk of depression and psychotic symptoms," added Louise Arseneault, a researcher at the Institute of Psychiatry, Psychology & Neuroscience at King's College London. "Health professionals need to be very aware of the possibility that women who experience mental health problems may also be the victims of domestic violence and vice versa. Given the prevalence of depression in these victims, we need to prevent these situations and take action. These acts of violence do more than leave physical damage; they leave psychological scars as well," concluded Dr. Arseneault.

http://www.sciencedaily.com/releases/2015/03/150331074443.htm

Greater odds of adverse childhood experiences in those with military service

July 23, 2014

Science Daily/The JAMA Network Journals

Men and women who have served in the military have a higher prevalence of adverse childhood events (ACEs), suggesting that enlistment may be a way to escape adversity for some. ACEs can result in severe adult health consequences such as posttraumatic stress disorder, substance use and attempted suicide.

The prevalence of ACEs among U.S. military members and veterans is largely unknown. ACEs can result in severe adult health consequences such as posttraumatic stress disorder, substance use and attempted suicide.

Authors compared the prevalence of ACEs among individuals with and without a history of military service using data from a behavioral risk surveillance system, along with telephone interviews, for an analytic sample of more than 60,000 people. ACEs in 11 categories were examined, including living with someone who is mentally ill, alcoholic or incarcerated, as well as witnessing partner violence, being physically abused, touched sexually or forced to have sex. Authors considered military service during the all-volunteer era (since 1973) vs. the draft era.

In the sample, 12.7 percent of the individuals reported military service, which was more common among men (24 percent) than women (2 percent). During the all-volunteer-era, men with military service had a higher prevalence of ACEs in all 11 categories than men without military service. For example, men with a history of military service had twice the prevalence of all forms of sexual abuse than their nonmilitary male peers: being touched sexually (11 percent vs. 4.8 percent), being forced to touch another sexually (9.6 percent vs. 4.2 percent) and being forced to have sex (3.7 percent vs. 1.6 percent). During the draft era, the only difference among men was in household drug use, where men with military service had a lower prevalence than men without military service.

Fewer differences in ACEs were found among women with and without military service than among men. Women with a history of military service in both eras had similar patterns of elevated odds for physical abuse, household alcohol abuse, exposure to domestic violence and emotional abuse compared with women who had not been in the military. Women who served in the military during the all-volunteer era also were more likely to report being touched sexually.

http://www.sciencedaily.com/releases/2014/07/140723162044.htm

Domestic violence victims more likely to take up smoking

- May 5, 2014

Science Daily/Columbia University's Mailman School of Public Health

One-third of women around the world have experienced physical or sexual violence at the hands of their intimate partners with consequences from post-traumatic stress disorder, anxiety, and depression, to sexually transmitted diseases, including HIV. Now, in a new study in 29 low-income and middle-income countries, researchers have identified yet another serious health risk associated with intimate partner violence: smoking.

The researchers examined the association between IPV and smoking among 231,892 women aged 15-29, using information collected in the Demographic and Health Surveys. Intimate partner violence is a serious problem in low- and middle-income countries. Reports of IPV in their study ranged from 9 to 63%. Employing a meta-analysis of country-level data that accounted for confounding factors like age, education, and household wealth, they found a 58% increased risk for smoking among the women who experienced IPV.

Women are thought to smoke tobacco to self-medicate to cope with stress from IPV. Many may be unaware of the serious health risks; tobacco kills half of its users, according to the World Health Organization.

The new study focused on low- and middle-income countries, where little research into the IPV-tobacco link has been done. However, the researchers say their results likely mean that the phenomenon is a global one. They cite among other papers, a 2008 study by Hee-Jin Jun et al that showed increased risk in American women.

http://www.sciencedaily.com/releases/2014/05/140505112540.htm