6 Reasons To Fall In Love With CBD

Guest post, Grace Hawkins

Ever since industrial hemp got legalized, there's been a significant influx of CBD (cannabidiol) products in the market. The industry is approximately worth more than a billion dollars and is still on a substantial rise. Online stores and convenience stores have already started selling CBD in various types and forms.

The Brightfield Research group has estimated that CBD markets are expected to have a 57% annual growth. Medical cannabis is facing acceptance and appreciation from the pharmaceutical industry. Medical professionals have discovered that CBD can naturally treat chronic pain, inflammation, epileptic seizures, and several other conditions. A survey from the Brightfield Group concluded that 42% of respondents turned to CBD products, and have stopped using pharmaceutical drugs or medication. The FDA has approved Epidiolex, a first-ever cannabis-derived drug for treating rare forms of epilepsy. Let us talk about the reason why you should consider falling in love with CBD. 

1.   Research Shows Promising Results

 Research in the field of cannabidiol has gone through numerous trials and studies.  Fortunately, the research has shown positive results. In 2017, the World Health Organization stated that CBD's pure state is well-tolerated by humans and animals. There are currently no risks and chances of physical dependence. Research shows a lot of encouraging results; therefore, the hype for CBD has reached another level. It might prove to be useful, especially on matters regarding epilepsy. It's always advisable to check in with your doctor before replacing any of your medication with CBD. 

2.   Can Alleviate Chronic Pain

 CBD affects ECS minutely. Instead, it activates or transforms other compounds present in the endocannabinoid system. If our body produces increased amounts of amandine, a compound responsible for regulating pain, it may reduce pain intensity. Studies have suggested that CBD can be used to treat chronic pain and inflammation. In 2017, the Health and Medical Division of US National Academies concluded that CBD is effective for neuropathic pain in adults and improves sclerosis spasticity symptoms.

3.   Can Improve Sleep Cycle

If you have insomnia, here's some good news for you. People consuming CBD have reported improvement in their sleep cycle when consumed an hour before bedtime. Therefore, it promotes a relaxing goodnight sleep. CBD is an excellent muscle relaxer as well. If your chronic pain keeps you awake at night, the best way to deal with the issues is by going for CBD edibles before bed. *Weed online canada Retailers can give you a greater insight into what options are available for consumption. 
(*This is not an endorsement by AV Stim, LLC implied or otherwise.)

4.   Its Legal Status

 For decades, all varieties of the cannabis plant have been considered Schedule I Substance. This means that they have high chances of abuse and no medical use. Substances with higher levels of THC are still illegal in the US. However, derivatives of the hemp plants have been legalized in many places. According to the Farm Bill of 2018, CBD containing a maximum of 0.3% of THC has been nationally legalized. Businesses have started selling as well as in many local stores. The ways of consumption vary from CBD edibles to oils and supplements. 

5.   Safe For Pets 

 Another quality of CBD is that it's safe for animals. Like humans, all animals have an endocannabinoid system. This system ensures that the cell receptors accept the benefits of CBD. It means that you and your pets can safely consume this natural remedy. Research has shown that CBD has helped alleviate symptoms of anxiety, insomnia, and osteoarthritis in their pets. 

6.   Reduced Mental Issues

 In recent times, CBD has drawn increasing interest as a treatment for many neuropsychology disorders. Fear and anxiety are natural responses that are necessary to cope with survival threats. But the excessive presence of concern can be a disability. According to studies, CBD shows positive results for curbing anxiety. Other than that, active research is being conducted, and experiments have suggested that it may decrease symptoms of schizophrenia. CBD is also considered to be useful for PTSD,  insomnia, and depression. It can be a great muscle relaxed as well. Those wanting to vape CBD can visit authorized smoke shop supplies retailers and reap all benefits.

Conclusion

 That's not all; it even shows promise to cure addiction among people. Since the benefits are immense, it has been positively received by the public. The CBD market is continuing to grow and has received great reviews from users. There's been an influx of CBD products in various forms, such as oils, bath bombs, edibles, supplements, dog treats, etc. The future of this industry is undoubtedly bright.

New approach to combatting anxiety states, pain and inflammation

June 6, 2017

Science Daily/University of Bern

Endogenous cannabinoids (endocannabinoids) play an important role in the brain and immune system. Bern researchers from the National Centre of Competence in Research (NCCR) "TransCure" have now found a new way to influence the endocannabinoid system. Anti-inflammatory, analgesic as well as anxiolytic effects could be achieved in an animal model.

Endocannabinoids are substances similar to fatty acids which are produced by the body. They activate specific cannabinoid receptors and among other things can exert anti-inflammatory or analgesic effects. Cannabis or tetrahydrocannabinol (THC) exhibit similar therapeutic effects in clinical use, but they are fraught with adverse effects. In contrast, endogenous cannabinoids are only produced in the cells when the body needs them, and therefore cannot be overdosed. The endocannabinoid system is considered promising as it uncovers new therapeutic options, for instance for disorders of the nervous system. For years, the research team led by Jürg Gertsch from the Institute of Biochemistry and Molecular Medicine at the University of Bern has been exploring the possibility to selectively activate endocannabinoids in the brain in order to treat neuropsychiatric disorders -- for example, anxiety states -- within the scope of the NCCR "TransCure" financed by the Swiss National Science Foundation (SNSF).

In cooperation with an international research team, the Bern research group led by Gertsch has now succeeded in blocking the transport route or endocannabinoids in the brain of mice for the first time by means of innovative inhibitors. This led to positive effects on the stress behaviour and immune system of mice. Anti-inflammatory, analgesic as well as anxiolytic effects have been observed. Although for several years it has been assumed that there is an endocannabinoid transport system in nerve cells and immune cells, this could now be shown for the first time. "I am convinced that in addition to the administration of exogenous cannabinoids, the endocannabinoid system will be specifically activated for therapeutic purposes in the future," says Gertsch. The study was published in the journal "Proceedings of the National Academy of Sciences (PNAS)."

Endocannabinoid Transport blocked

In cooperation with chemists from the Swiss Federal Institute of Technology/ETH Zurich (research group led by Prof. Karl-Heinz Altmann) and the industry, hundreds of endocannabinoid transport inhibitors were synthesised in order to develop ideal pharmacological properties. The researchers were inspired for these inhibitors by a natural substance from the purple coneflower (Echinacea purpurea), a medicinal plant which is frequently utilised for colds and partially has an effect on the endocannabinoid system. The newly developed inhibitors block the uptake of endocannabinoids through the membrane of cells. As a result, cannabinoid receptors on nerve and immune cells are activated, which leads to a "brake" in the brain and in the immune system upon stress and in inflammatory disorders, restoring the physiological equilibrium.

New perspectives for new medicines

Andrea Chicca, lead author of the study from the group led by Prof. Gertsch, is confident that the molecular mechanism of endocannabinoid transporter can be elucidated in the coming years: "Then nothing stands in the way for the development of new medicines." Thanks to the new findings from the study, already now substances can be made which differ from previous drugs as they specifically activate the endogenous cannabinoids in the brain. The researchers see great potential in the field of stress-related disorders, because endocannabinoids regulate important stress hormones and restore the equilibrium in the brain.

https://www.sciencedaily.com/releases/2017/06/170606090806.htm